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ANO1-IN-1

SKU: orb2900831

Description

ANO1-IN-1 (Compound 9c) is a selective ANO1 channel blocker with an IC50 of 2.56 μM and 15.43 μM against ANO1 and ANO2, respectively. ANO1-IN-1 suppresses strongly proliferation of glioblastoma cells.

Research Area

Neuroscience

Images & Validation

Key Properties

CAS Number407587-01-3
MW336.49
Purity>98% (HPLC)
FormulaC18H28N2O2S
SMILESC(N)(=O)C=1C2=C(SC1NC(C(C)(C)C)=O)CC(C(C)(C)C)CC2
TargetCRAC Channel
SolubilityIn Vitro: DMSO : 250 mg/mL (742.96 mM; Ultrasonic )

Bioactivity

In Vitro
ANO1-IN-1 (Compound 9c) (10 μM) significantly suppresses migration and invasion of U251 cells. ANO1-IN-1 and TMZ combination brings about remarkable synergistic effects in suppressing proliferation of GBM cells.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • ANO1-IN-1 [orb1688985]

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    407587-01-3

    336.49

    C18H28N2O2S

    5 mg, 50 mg, 100 mg, 10 mg, 25 mg
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Protocol Information

ANO1-IN-1 (orb2900831)

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Available Sizes

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500 mg
5 mg
¥ 1,040.00
10 mg
¥ 1,300.00
25 mg
¥ 2,210.00
50 mg
¥ 3,120.00
100 mg
¥ 4,420.00