GDF15/MIC1 Antibody

SKU: orb1805630

Description

Anti-GDF15 / MIC1 Reference Antibody is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Images & Validation

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Tested Applications	ELISA, FA, FACS, In vivo
Reactivity	Human

Key Properties

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Clonality	Monoclonal
Target	GDF15 / MIC1
Source/Expression System	CHO
Molecular Weight	145.4 kDa
Purity	>95%
Purification	Protein A
Endotoxin	<0.001 EU/ug
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	100 mM Proline/Acetic acid 20mM Arginine pH 5.0
Concentration	Batch dependent
Disclaimer	For research use only

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Anti-GDF15 / MIC1 Reference Antibody (ponsegromab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

The purity of Anti-GDF15 / MIC1 Reference Antibody (ponsegromab)is more than 99.55% ;determined by SEC-HPLC.

Immobilized human GDF15 His at 2 μg/mL can bind Anti-GDF15 / MIC1 Reference Antibody (ponsegromab);EC50=0.01861μg/mL.

Anti-IL-6Ra / CD126 Reference Antibody (vobarilizumab) Proliferation inhibition using TF-1 Cell. The maximum proliferation inhibition rate is about 80%.

Quick Database Links

Gene Symbol

GDF15 / MIC1

UniProt

Q99988

UniProt Details

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No UniProt data available

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Protocol Information

FACS

Fluorescence-Activated Cell Sorting (FC, Flow cytometry)

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ELISA

Enzyme-linked Immunosorbent Assay (EIA)

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