CD180 Antibody (APC)

SKU: orb154439

Description

Mouse monoclonal antibody conjugated to APC which recognizes CD180 that belongs to the toll-like receptor family. It is expressed on mature B cells, monocytes/macrophages and dendritic cells. CD180 is a signal transduction molecule and plays a role in regulation of B cell growth and death and also play a role in the innate immune response to bacterial lipopolysaccharide, through co-operation with MD-1 and TLR4.

Research Area

Epigenetics, Immunology

Images & Validation

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Tested Applications	FC
Reactivity	Human
Application Notes	Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Key Properties

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Antibody Type	Primary Antibody
Clonality	Monoclonal
Isotype	Mouse IgG1 kappa
Clone No.	G28-8
Immunogen	Human tonsillar B cells
Target	CD180
Purification	Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Conjugation	APC

Storage & Handling

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Storage	Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Buffer/Preservatives	Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Disclaimer	For research use only

Alternative Names

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LY64, Ly78, RP105, Bgp95

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Flow cytometry analysis (surface staining) of human peripheral blood cells with anti-CD180 (G28-8) APC.

Quick Database Links

Gene Symbol

CD180

UniProt

Q99467

NCBI Gene ID

4064

UniProt Details

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No UniProt data available

NCBI Gene Details

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No NCBI Gene data available

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Protocol Information

Flow Cytometry

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