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Anti-inflammatory agent 41

SKU: orb2566991

Description

This small molecule anti-inflammatory agent (13a) potently suppresses LPS-induced IL-6 and TNF-α expression in J774A.1, THP-1, and LX-2 cells and blocks NF-κB pathway activation. It is a useful research tool for studying inflammation in macrophage and hepatic stellate cell models, applicable in both in vitro and in vivo experimental systems.

Research Area

Cell Biology, Immunology & Inflammation, Signal Transduction

Images & Validation

Key Properties

CAS Number2896204-90-1
MW543.57
FormulaC33H25N3O5
SMILESC(NC1=CC=C(OC=2C3=C(C=C(OC)C(OC)=C3)N=CC2)C=C1)(=O)C4=CN(C=5C(C4=O)=CC=CC5)C6=CC=CC=C6
TargetTNF,NF-κB,Interleukin

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Anti-inflammatory agent 41 (orb2566991)

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