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AS1810722

SKU: orb1298418

Description

AS1810722

Research Area

Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number909561-15-5
MW477.51
Purity99.13%
FormulaC25H25F2N7O
SMILESNC(=O)CN1CCN(CC1)c1ccc(Nc2ncc3ccn(Cc4cc(F)cc(F)c4)c3n2)cc1
TargetSTAT,Cytochromes P450
SolubilityDMSO:62.5 mg/mL (130.89 mM)

Bioactivity

Target IC50
STAT6:1.9 nM
In Vitro
AS1810722 showed potent STAT6 Inhibition and a good CYP3A4 Inhibition profile.?AS1810722 also inhibited in vitro Th2 differentiation without affecting type 1 helper T (Th1) cell differentiation and eosinophil infiltration in an antigen-induced mouse asthmatic model after oral administration.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

STAT, STAT6, CYPs, CYP3A4, Cytochrome P450, allergic, AS1810722, AS-1810722, AS 1810722, asthma, orally, infiltration, IL-4, inhibit, Inhibitor, IFN-γ, eosinophil

Similar Products

  • AS1810722 [orb1217490]

    >98% (HPLC)

    909561-15-5

    477.5

    C25H25F2N7O

    10 mg, 25 mg, 50 mg, 5 mg, 1 g, 500 mg, 200 mg, 100 mg
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Key Properties

No computed properties available.

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AS1810722 (orb1298418)

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Available Sizes

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1 mg
¥ 1,950.00
5 mg
¥ 3,770.00
1 ml x 10 mM (in DMSO)
¥ 3,900.00
10 mg
¥ 5,460.00
25 mg
¥ 8,840.00
50 mg
¥ 12,220.00
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