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AZD1940

SKU: orb1698237

Description

AZD1940 is a potent, orally active cannabinoid receptor agonist with high affinity for both CB1 and CB2 receptors. It is a research compound utilized in preclinical studies, particularly for investigating mechanisms and potential treatments for orofacial pain in vivo.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number881413-29-2
MW413.52
Purity99.43%
FormulaC20H29F2N3O2S
SMILESCCS(=O)(=O)Nc1ccc2n(CC3CCC(F)(F)CC3)c(nc2c1)C(C)(C)C
TargetCannabinoid Receptor
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.98 mM);DMSO:90 mg/mL (217.64 mM)

Bioactivity

Target IC50
CB2 receptor (human):9.06 (pKi)|CB1 receptor (human):7.93 (pKi)
In Vivo
After given orally to human, the mean maximum plasma concentration (Cmax) for AZD1940 800 mg was 9.3 nmol/L . The mean concentration over post-dose eight hours for AZD1940 was 236 nmol.h/L.
In Vitro
AZD1940 demonstrates high binding affinity towards the CB1 and CB2 receptors in humans, rats, and mice, exhibiting full agonism at both receptor types across these species.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CannabinoidReceptor, Cannabinoid Receptor, AZD1940, AZD-1940, AZD 1940, hCB2, hCB1, UNII-0J0035E9FT
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

AZD1940 (orb1698237)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
¥ 2,340.00
5 mg
¥ 4,810.00
1 ml x 10 mM (in DMSO)
¥ 5,330.00
10 mg
¥ 7,930.00
25 mg
¥ 12,220.00
50 mg
¥ 16,510.00
100 mg
¥ 22,230.00
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