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B2

SKU: orb1305874

Description

This small molecule, known as B2 or Linazolamide intermediate B impurity 2, has been shown to induce protein aggregation in cellular models of Huntington's and Parkinson's disease. It serves as a research tool for studying neurodegenerative disease mechanisms in vitro, particularly related to pathological inclusion formation.

Research Area

Epigenetics & Chromatin, Metabolism Research, Molecular Biology

Images & Validation

Key Properties

CAS Number115687-05-3
MW396.83
FormulaC20H17ClN4O3
SMILES[O-][N+](=O)c1ccc(N2CCN(CC2)C(=O)c2ccc(Cl)cc2)c2cccnc12
TargetHIF/HIF Prolyl-Hydroxylase
SolubilityH2O:2 mg/mL (5.04 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble);DMSO:50 mg/mL (126 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Sirtuin, 5-[4-(4-Chlorobenzoyl)-1-piperazinyl]-8-nitroquinoline, B2, B-2, B 2, CPNQ, Huntington's diseases, HIF/HIFProlylHydroxylase, HIF/HIF ProlylHydroxylase, HIF Prolyl-Hydroxylase, HIF ProlylHydroxylase, HIF, Inhibitor, HIFProlylHydroxylase, Linazolamide intermediate B impurity 2, inhibit, Parkinson's diseases

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

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1 mg
$ 80.00
2 mg
$ 100.00
5 mg
$ 140.00
10 mg
$ 190.00
25 mg
$ 300.00
50 mg
$ 400.00
100 mg
$ 560.00
200 mg
$ 740.00
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