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BC-1293

SKU: orb2664112

Description

BC-1293 is an inhibitor of the E3 ligase subunit FBXO24 that acts by disrupting the interaction between FBXO24 and aspartyl-tRNA synthetase (DARS2). BC-1293 treatment results in increased levels of DARS2, showing its capacity to stabilize this essential enzyme. Furthermore, BC-1293 elevates levels of cytokines including IL-1β, IL-9, MIP-2, and TNF-α in murine models, thereby demonstrating immunostimulatory activity with potential relevance to immune modulation research.

Research Area

Protein Biochemistry

Images & Validation

Key Properties

CAS Number1219395-86-4
MW492.59
Purity98.40%
FormulaC26H28N4O4S
SMILESO=C(N1CC=C(C=2C=CC=CC2)CC1)C(NS(=O)(=O)C=3C=C(C=CC3C)C4=NOC(=N4)C5CC5)C
TargetE1/E2/E3 Enzyme

Storage & Handling

Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

BC1293
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Protocol Information

BC-1293 (orb2664112)

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Available Sizes

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1 mg
¥ 3,120.00
5 mg
¥ 6,890.00
10 mg
¥ 9,620.00
25 mg
¥ 14,560.00
50 mg
¥ 19,890.00
100 mg
¥ 26,000.00
200 mg
¥ 35,360.00
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