Bepridil hydrochloride

SKU: orb1221000

Description

Bepridil is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX) sodium channels and cardiac sarcolemmal KATP channels.(In Vitro):Bepridil hydrochloride is a calcium channel blocker, with antianginal activity.(In Vivo):Bepridil hydrochloride (21 mg/kg) reduces heart rate and mean arterial pressure, decreases the mean coronary vascular resistance and increases stroke volume in rats.

Research Area

Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	68099-86-5
MW	403
Purity	>98% (HPLC)
Formula	C₂₄H₃₅ClN₂O
SMILES	Cl.CC(C)COCC(CN(Cc1ccccc1)c1ccccc1)N1CCCC1
Target	Calcium Channel
Solubility	DMSO: 130 mg/mL (322.58 mM)

Bioactivity

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In Vivo	Bepridil hydrochloride (21 mg/kg) reduces heart rate and mean arterial pressure, decreases the mean coronary vascular resistance and increases stroke volume in rats.
In Vitro	Bepridil hydrochloride is a calcium channel blocker, with antianginal activity.

Storage & Handling

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Storage	Storage temperature: -20°C. Stability: ≥ 2 years
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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CERM 1978

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Quick Database Links

Gene Symbol

Calcium Channel

Protocol Information

Find More Protocols

CAS Number:	64706-54-3
MW:	366.54
Formula:	C₂₄H₃₄N₂O

Purity:	99.45% (May vary between batches)
CAS Number:	68099-86-5
MW:	403
Formula:	C₂₄H₃₅ClN₂O