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CCR5 (C) Antibody, Rabbit Polyclonal

SKU: orb67200

Description

Rabbit polyclonal to CCR5.C-C chemokine receptor type 5 (CCR5) is a multi-pass membrane protein that belongs to the Gproteincoupled receptor 1 family. It is a receptor for a number of inflammatory CC-chemokinesincluding MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasingthe intracellular calcium ion level. It may play a role in the control of granulocytic lineage proliferationor differentiation. CCR5 acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.Genetic variation in CCR5 is associated with susceptibility to diabetes mellitus insulin-dependent type22 (IDDM22).

Research Area

Immunology & Inflammation

Images & Validation

Tested ApplicationsWB
Dilution RangeWB:1:1000-1:3000
ReactivityHuman

Key Properties

HostRabbit
ClonalityPolyclonal
ImmunogenC-terminal region of human CCR5
Molecular Weight41
PurityAffinity purification
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives0.01% NaN3
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

anti-CCR5 antibody,anti-CC chemokine receptor type 5 antibody,anti-CC CKR5 antibody,anti-CCCKR5 antibody,anti-CCR5 antibody,anti-CCR5 antibody,anti-CHEMR13 antibody,anti-HIV1 fusion coreceptor antibody,anti-CD195 antibody,anti-CMKBR5 antibody

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UniProt Details

No UniProt data available

Protocol Information

WB
Western Blot (IB, immunoblot)
View Protocol

Available Sizes

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100 μl
$ 440.00
Choose Conjugation or Carrier Free Version
Free Secondary Antibody (20 ul)0/0

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DispatchUsually dispatched within 5-10 working days.
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