CCR5 (C) Antibody, Rabbit Polyclonal

SKU: orb67200

Description

Rabbit polyclonal to CCR5.C-C chemokine receptor type 5 (CCR5) is a multi-pass membrane protein that belongs to the Gproteincoupled receptor 1 family. It is a receptor for a number of inflammatory CC-chemokinesincluding MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasingthe intracellular calcium ion level. It may play a role in the control of granulocytic lineage proliferationor differentiation. CCR5 acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.Genetic variation in CCR5 is associated with susceptibility to diabetes mellitus insulin-dependent type22 (IDDM22).

Research Area

Epigenetics, GPCR, Infectious Diseases, Neuroscience, Signaling Pathways

Images & Validation

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Item 1 of 1

Tested Applications	WB
Dilution range	WB:1:1000-1:3000
Reactivity	Human

Key Properties

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Host	Rabbit
Clonality	Polyclonal
Immunogen	C-terminal region of human CCR5
Molecular Weight	41
Purity	Affinity purification
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives	0.01% NaN3
Disclaimer	For research use only

Alternative Names

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anti-CCR5 antibody,anti-CC chemokine receptor type 5 antibody,anti-CC CKR5 antibody,anti-CCCKR5 antibody,anti-CCR5 antibody,anti-CCR5 antibody,anti-CHEMR13 antibody,anti-HIV1 fusion coreceptor antibody,anti-CD195 antibody,anti-CMKBR5 antibody

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Western blot analysis of total cell extracts from mouse brain using CCR5 antibody

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UniProt

P51681

UniProt Details

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No UniProt data available

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Protocol Information

Western Blot (IB, immunoblot)

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