Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

CD27 Antibody

SKU: orb1825893

Description

Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis.

Research Area

Immunology & Inflammation; Cell Biology

Images & Validation

Tested ApplicationsIHC-P
Dilution RangeImmunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
ReactivityHuman
Application Notes
Optimal dilution of the CD27 antibody should be determined by the researcher.

Key Properties

Antibody TypePrimary Antibody
HostMouse
ClonalityRecombinant
IsotypeMouse IgG1, kappa
Clone No.rLPFS2/8837
ImmunogenA recombinant human CD27 protein fragment (within amino acids 28-170) was used as the immunogen for the CD27 antibody.
PurificationProtein A/G affinity
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • CD27 Antibody [orb640041]

    ELISA,  FACS,  IF,  IHC-P

    Human

    Mouse

    Monoclonal

    Unconjugated

    100 μg, 20 μg
  • CD27 Antibody [orb2644026]

    ELISA,  FACS,  IF,  IHC-P

    Human

    Mouse

    Monoclonal

    Unconjugated

    100 μg
  • CD27 Antibody [orb757382]

    ELISA,  FC,  IHC,  WB

    Human

    Rabbit

    Monoclonal

    Unconjugated

    100 μg, 50 μg, 500 μg, 10 μg
  • Human Tumor Necrosis Factor Receptor Superfamily, Member 7 (TNFRSF7) ELISA Kit [orb778889]

    Human

    0.16-10 ng/mL

    0.063 ng/mL

    48 T, 96 T
  • CD27 Antibody [orb1410339]

    IHC,  WB

    Human

    Mouse

    Monoclonal

    Unconjugated

    20 μg, 100 μg, 100 μg (without BSA and Azide)
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

UniProt Details

No UniProt data available

Protocol Information

IHC-P
Immunohistochemistry Paraffin
View Protocol

Available Sizes

Select a size below

20 μg
$ 370.00
100 μg
$ 750.00
Choose Conjugation or Carrier Free Version
Free Secondary Antibody (20 ul)0/0

Please add an antibody product to your cart first.

DispatchUsually dispatched within 5-10 working days
Bulk Enquiry