Clozapine N-oxide dihydrochloride

SKU: orb1745121

Description

Clozapine N-oxide dihydrochloride is a blood-brain barrier permeable agonist for the chemogenetic DREADD receptors hM3Dq and hM4Di. It is a key research tool for targeted neuronal manipulation in studies of neural circuits, behavior, and diseases, applicable in both in vitro and in vivo experimental models.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

−

Key Properties

−

CAS Number	2250025-93-3
MW	415.74
Purity	98.11%
Formula	C₁₈H₂₁Cl₃N₄O
SMILES	C[N+]1(CCN(C2=NC3=CC(Cl)=CC=C3NC4=C2C=CC=C4)CC1)[O-].Cl.Cl
Target	Dopamine Receptor,AChR,Drug Metabolite,Cholinesterase (ChE)
Solubility	10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (24.05 mM);H2O:50 mg/mL (120.27 mM);DMSO:200 mg/mL (481.07 mM)

Storage & Handling

−

Storage	store under nitrogen,store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

−

AChE, Clozapine N-oxide, Clozapine N-oxide Dihydrochloride

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Compound Identifiers

PubChem CID

171360898 ↗

Key Properties

−

No computed properties available.

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols