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CMF019

SKU: orb1710022

Description

CMF019 is a G protein-biased, potent agonist of the Apelin receptor (APJ), demonstrating high-affinity binding across human, rat, and mouse orthologs. This small molecule is a valuable research tool for investigating APJ signaling in cardiovascular and metabolic studies, applicable in both in vitro and in vivo experimental models.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1586787-08-7
MW455.61
Purity99.50%
FormulaC25H33N3O3S
SMILESCCC(CC)n1c(Cc2cccs2)nc2cc(ccc12)C(=O)N[C@@H](CC(C)C)CC(O)=O
TargetApelin receptor
SolubilityDMSO:255 mg/mL (559.69 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.97 mM)

Bioactivity

Target IC50
Apelin receptor (mouse):8.71 (pKi)|Apelin receptor (rat):8.49 (pKi)|Apelin receptor (human):8.58 (pKi)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CMF 019, CMF019, CMF-019, Apelinreceptor, Apelin receptor, mouse Apelin receptor, human Apelin receptor, rat Apelin receptor
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

CMF019 (orb1710022)

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% DMSO +
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% Tween 80 +
%

Available Sizes

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1 mg
¥ 2,080.00
1 ml x 10 mM (in DMSO)
¥ 3,770.00
5 mg
¥ 3,770.00
10 mg
¥ 5,980.00
25 mg
¥ 9,360.00
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