Cart summary

You have no items in your shopping cart.

CU-CPT17e

SKU: orb1309807

Description

CU-CPT17e

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number2109805-75-4
MW504.49
Purity99.18%
FormulaC27H24N2O8
SMILES[O-][N+](=O)c1ccc(COc2cc3OC4(CCOCC4)C=Cc3cc2OCc2ccc(cc2)[N+]([O-])=O)cc1
TargetTLR
SolubilityDMSO:2 mg/mL (3.96 mM)

Bioactivity

In Vitro
The first small molecule 17e (CU-CPT17e) capable of simultaneously activating TLRs 3, 8, and 9. Biochemical studies demonstrated that 17e could induce a strong immune response via the production of various cytokines in human monocytic THP-1 cells. Furthermore, 17e inhibited the proliferation of HeLa cancer cells by triggering apoptosis and arresting the cell cycle at the S phase. These results showcase potential therapeutic applications of 17e in both vaccine adjuvants and anticancer therapies based on multi-TLR activation.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Toll-like Receptor (TLR), TLR9, TLR8, TLR3, TLR, Inhibitor, inhibit, CU CPT17e, CUCPT17e, CU-CPT17e, CU-CPT-17e

Similar Products

  • CU-CPT17e [orb1218458]

    >98% (HPLC)

    2109805-75-4

    504.5

    C27H24N2O8

    200 mg, 5 mg, 10 mg, 50 mg, 100 mg, 1 g, 500 mg, 25 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

CU-CPT17e (orb1309807)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
¥ 3,380.00
5 mg
¥ 6,370.00
10 mg
¥ 8,970.00
25 mg
¥ 13,390.00
50 mg
¥ 18,590.00
100 mg
¥ 24,830.00
DispatchUsually dispatched within 3-5 working days
Bulk Enquiry