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CU-CPT9b

SKU: orb1299939

Description

CU-CPT9b is a potent and selective TLR8 antagonist with a Kd of 21 nM. It inhibits R-848-induced NF-κB activation in TLR8-overexpressing HEK-Blue cells with an IC50 of 0.7 nM. This tool compound is valuable for in vitro studies investigating TLR8 signaling and its role in autoimmune, inflammatory, and antiviral research.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number2162962-69-6
MW251.28
Purity98.10%
FormulaC16H13NO2
SMILESCc1cc(ccc1O)-c1ccnc2cc(O)ccc12
TargetTLR
SolubilityDMSO:100 mg/mL (397.96 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (15.92 mM)

Bioactivity

Target IC50
TLR8:0.7 nM (IC50)|TLR8:21 nM (Kd)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

CUCPT9b, CU-CPT9b, CU-CPT-9b, CU CPT9b, Inhibitor, inhibit, TLR8-specific antagonist 1, TLR8, TLR, Toll-like Receptor (TLR)

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    2162962-69-6

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    C16H13NO2

    2 mg, 5 mg, 10 mg, 50 mg, 100 mg, 1 g, 500 mg, 200 mg, 25 mg
Quality Guarantee

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Key Properties

No computed properties available.

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CU-CPT9b (orb1299939)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
¥ 1,170.00
5 mg
¥ 1,820.00
1 ml x 10 mM (in DMSO)
¥ 2,080.00
10 mg
¥ 2,730.00
25 mg
¥ 4,160.00
50 mg
¥ 5,720.00
100 mg
¥ 8,190.00
200 mg
¥ 11,440.00
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