CYM 5442 hydrochloride

SKU: orb3033108

Description

CYM5442 hydrochloride is a potent, highly-selective and orally active sphingosine 1-phosphate (S1P1) receptor agonist with an EC50 of 1.35 nM. CYM5442 hydrochloride is inactive against S1P2, S1P3, S1P4, and S1P5. CYM5442 hydrochloride activates S1P1-dependent p42/p44-MAPK phosphorylation. CYM5442 exerts retinal neuroprotection. CYM5442 hydrochloride can easily penetrate the central nervous system (CNS).

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Key Properties

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CAS Number	1783987-80-3
MW	445.939125061035
Purity	>98%
Formula	C₂₃H₂₈CLN₃O₄
SMILES	Cl.O1C(C2C=CC(=C(C=2)OCC)OCC)=NC(C2=CC=CC3=C2CCC3NCCO)=N1

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Disclaimer	For research use only

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