Cynomolgus IL-7 R alpha / CD127 Protein, His Tag (MALS verified)

SKU: orb3158164

Description

Interleukin-7 receptor subunit alpha (IL7Ra) is also known as CD antigen CD127, which belongs to the type I cytokine receptor family and type 4 subfamily. IL7Ra /CD127 contains 1 fibronectin type-III domain. IL7Ra /CD127 is expressed on various cell types, including naive and memory T cells and many others. IL7Ra /CD127 is receptor for interleukin-7 and also acts as a receptor for thymic stromal lymphopoietin (TSLP). The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.

Research Area

Immunology & Inflammation

Images & Validation

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Application Notes	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.2 kDa. The protein migrates as 35-50 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

Key Properties

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Expression System	HEK293
Target	IL-7 R alpha
Reactivity	Monkey
Tag	C-10×His
Expression Region	Glu 21 - Pro 240
Endotoxins	1.0 EU per μg
Conjugation	Unconjugated
MW	27.2 kDa
Purity	90%

Storage & Handling

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Storage	-20°C
Form/Appearance	Powder
Buffer/Preservatives	PBS, pH 7.4
Expiration Date	6 months from date of receipt.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

IL-7 R alpha

RefSeq:Q38IC7

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

RefSeq	Q38IC7

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Protocol Information

Protein Handling and Storage Guide

Protein Handling Guide

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