diABZI STING agonist-1

SKU: orb1983489

Description

diABZI STING agonist-1 is a potent and selective small molecule agonist of the STING receptor, demonstrating potential antitumor and immunomodulatory activity. It is widely used in cancer immunology research to study STING pathway activation, showing efficacy in both cellular assays and in vivo tumor models.

Research Area

Immunology & Inflammation

Images & Validation

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Key Properties

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CAS Number	2138299-33-7
MW	849.94
Purity	97.50%
Formula	C₄₂H₅₁N₁₃O₇
SMILES	O=C(C1=CC(C)=NN1CC)N=C2N(C3=C(OC)C=C(C(N)=O)C=C3N2)C/C=C/CN4C5=C(OCCCN6CCOCC6)C=C(C(N)=O)C=C5NC4=NC(C7=CC(C)=NN7CC)=O
Target	STING
Solubility	10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (3.88 mM);H2O:< 1 mg/mL (Insoluble);DMSO:80 mg/mL (94.12 mM)

Bioactivity

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In Vivo	In Wild and Sting −/− C57Blk6 mice, diABZI STING agonist-1 ( 2.5 mg/kg ; subcutaneous injection ; 2.5 mg/kg ) activated secretion of IFNβ, IL-6, TNF, and CXCL1 in wild-type but not Sting −/− mice. Read more...

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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STING

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Compound Identifiers

PubChem CID

131986624 ↗

Key Properties

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No computed properties available.

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