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Dopamine hydrochloride

SKU: orb1224426

Description

Dopamine HCl is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number62-31-7
MW189.64
Purity>98% (HPLC)
FormulaC8H12ClNO2
SMILESCl.NCCC1=CC(O)=C(O)C=C1
Target5-HT Receptor
SolubilityWater: 38 mg/mL (200.37 mM); DMSO: 38 mg/mL (200.37 mM)

Bioactivity

In Vivo
Animal model: Syngeneic C3Heb/FeJ mice with MOT ascites tumors. Dosage: 50 mg/kg. Administration: i.p. injection; 7 days. Result: Corresponding to ~5% of the median lethal dose (LD50) in mice) beginning at 24 hours after tumor-cell injection and continuing daily for 7 days.
In Vitro
Cell Proliferation Assay Cell line: HUVECs. Concentration: 1 μM. Incubation time: 24 hours. Result: Inhibited VPF/VEGF-induced HUVEC proliferation specifically through its D2 receptor.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

DA | KW 3160 | 3-hydroxy Tyramine

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Protocol Information

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