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E3 ligase Ligand 27

SKU: orb2564572

Description

E3 Ligase Ligand 27 is a cereblon-binding moiety used to construct PROTAC Bcl-2/Bcl-xL Degrader-1. This bifunctional degrader is a research tool for targeted protein degradation, enabling the study of Bcl-2 family proteins in cancer models both in vitro and in vivo.

Research Area

Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number3034204-25-3
MW558.69
FormulaC28H38N4O6S
SMILESC(NC(=O)[C@H]1N(C([C@@H](NC(OC(C)(C)C)=O)C(C)(C)C)=O)C[C@H](O)C1)C=2C=C3C(C4=C(N=CS4)CCO3)=CC2
TargetLigands for E3 Ligase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information