Emapalumab Antibody

SKU: orb1980701

Description

Emapalumab (NI-0501) is an IgG1 monoclonal antibody that humanizes human monoclonal antibodies against interferon gamma, blocking its binding to cell surface receptors and activating inflammatory signaling. Emapalumab has a high binding force (Kd=1.4 pM) to free IFN-γ and to IFN-γ bound to its receptor. Emapalumab can be used in the study of hemophagocytic lymphohistiocytosis (HLH).

Research Area

Immunology & Inflammation, Neuroscience

Images & Validation

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Key Properties

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CAS Number	1709815-23-5
MW	145.22 kDa
Purity	97.56% (SEC-HPLC)
Target	COX,IFNAR

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Disclaimer	For research use only

Alternative Names

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IFN-γ, Emapalumab, NI 0501, NI0501, NI-0501

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Gene Symbol

COX,IFNAR

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