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EPI-X4 TFA

SKU: orb1980040

Description

EPI-X4 is a human serum albumin-derived peptide antagonist of CXCR4. It inhibits CXCL12-induced calcium flux, receptor internalization, and cell migration in vitro, and reduces inflammatory cell infiltration in a mouse model of airway hypereosinophilia. Elevated urinary EPI-X4 in chronic kidney disease patients also suggests its potential as a biomarker.

Images & Validation

Key Properties

MW1830.18
FormulaC84H144N22O23.XCF3COOH
SMILES[H]N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@]([C@@H](C)O)([H])C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N1CCC[C@H]1C(N[C@@H](CCC(N)=O)C(N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@]([C@@H](C)O)([H])C(N2CCC[C@H]2C(N[C@]([C@@H](C)O)([H])C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CC=C(O)C=C3)=O)=O)=O.OC(C(F)(F)F)=O

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Key Properties

No computed properties available.

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EPI-X4 TFA (orb1980040)

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