FK-866 Hydrochloride

SKU: orb2647445

Description

Daporinad, also known as APO-866 and FK866, is a small molecule with potential antineoplastic and antiangiogenic activities. NMPRTase inhibitor APO866 binds to and inhibits nicotinamide phosphoribosyltransferase (NMPRTase), inhibiting the biosynthesis of nicotinamide adenine dinucleotide (NAD+) from niacinamide (vitamin B3), which may deplete energy reserves in metabolically active tumor cells and induce tumor cell apoptosis. In addition, this agent may inhibit tumor cell prioduction of vascular endothelial growth factor (VEGF), resulting in the inhibition of tumor angiogenesis.

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Key Properties

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CAS Number	2727965-45-7
MW	427.966905117035
Purity	>98%
Formula	C₂₄H₃₀CLN₃O₂
SMILES	C(C1C=CC=CC=1)(N1CCC(CCCCNC(=O)/C=C/C2=CN=CC=C2)CC1)=O.Cl

Storage & Handling

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Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

78243733 ↗

Key Properties

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No computed properties available.

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