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Description

This small molecule agonist activates immune signaling via TLR2/6 and potentially TLR10, leading to NF-κB activation and the production of pro-inflammatory cytokines like IL-8 and TNF-α in vitro. It is used in research areas such as innate immunity, cancer immunology, and inflammation, where it can synergize with IFNγ to enhance CXCL10 release from cells.

Research Area

Immunology & Inflammation, Infectious Disease & Virology

Images & Validation

Key Properties

TargetAntibiotic,TLR
CAS Number322455-70-9
MW1666.16
FormulaC84H140N14O18S
SMILESC([C@H](CC1=CN=CN1)NC([C@@H](NC(=O)[C@H]2N(C([C@@H](NC(CNC([C@H](CSCC(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)N)=O)=O)CC(O)=O)=O)CCC2)CCCCN)=O)(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(O)=O)=O)CO)=O)CCCCN)=O)CCC3

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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FSL-1 (orb1983807)

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