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GeA-69

SKU: orb1301822

Description

GeA-69

Research Area

Epigenetics & Chromatin, Molecular Biology

Images & Validation

Key Properties

CAS Number2143475-98-1
MW300.35
Purity99.85%
FormulaC20H16N2O
SMILESCC(=O)Nc1ccccc1-c1cccc2c3ccccc3[nH]c12
TargetPARP
SolubilityDMSO:120 mg/mL (399.53 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (13.32 mM)

Bioactivity

Target IC50
PARP14:0.86 μM (Kd, in ITC assays)
In Vitro
The macrodomain recruitment was significantly decreased in cells pre-treated with 50 μM GeA-69 and completely prevented in cells exposed to 50 μM GeA-69.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

cytotoxicity, DNA damage repair mechanism, cell permeable, HeLa, HEK293, intact cell, Inhibitor, GeA 69, GeA69, GeA-69, inhibit, poly ADP ribose polymerase, PARP, PARP14, U-2 OS

Similar Products

  • GeA-69 [orb1221005]

    >98% (HPLC)

    2143475-98-1

    300.4

    C20H16N2O

    5 mg, 100 mg, 50 mg, 1 g, 500 mg, 200 mg, 10 mg, 25 mg
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Key Properties

No computed properties available.

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Protocol Information

GeA-69 (orb1301822)

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% DMSO +
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% Tween 80 +
%

Available Sizes

Select a size below

5 mg
¥ 1,040.00
1 ml x 10 mM (in DMSO)
¥ 1,170.00
10 mg
¥ 1,300.00
25 mg
¥ 2,080.00
50 mg
¥ 3,250.00
100 mg
¥ 4,290.00
200 mg
¥ 5,980.00
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