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GPR35 agonist 3

SKU: orb1744688

Description

GPR35 agonist 3 is a synthetic ligand that activates GPR35 with an EC₅₀ of 1.4 µg in a β-arrestin assay. This compound serves as a research tool for investigating the receptor's role in pathologies such as cancer, type 2 diabetes, and cardiovascular disease, facilitating both in vitro and in vivo experimental studies.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number123021-85-2
MW279.27
Purity98.80%
FormulaC12H9NO5S
SMILESOC(=O)COC1=CC=C(\C=C2\SC(=O)NC2=O)C=C1
TargetGPCR,Arrestin
SolubilityDMSO:100 mg/mL (358.08 mM)

Bioactivity

Target IC50
GPR35:1.4 μM (EC50)|GPR35:0.0508 μM (Ki)|GPR35:0.349 μM

Storage & Handling

Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

β-arrestin, GPR35

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Key Properties

No computed properties available.

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Protocol Information

GPR35 agonist 3 (orb1744688)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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2 mg
¥ 1,040.00
5 mg
¥ 1,300.00
10 mg
¥ 1,820.00
25 mg
¥ 3,120.00
50 mg
¥ 4,550.00
100 mg
¥ 7,020.00
DispatchUsually dispatched within 6-8 weeks
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