GSK-3β inhibitor 17

SKU: orb2646324

Description

GSK-3β Inhibitor 17 (compound 5 n) reduces the expression of p-p65 and KIM-1 proteins in a dose-dependent manner (16, 32, 64 µM) induced by cisplatin. Additionally, at a concentration of 32 µM, it decreases the levels of TNF-α, IL-1β, IL-6, and MCP-1 mRNA in an acute kidney injury (AKI) model of HK-2 cells triggered by cisplatin.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

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Key Properties

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CAS Number	2521624-67-7
MW	617.58
Formula	C₂₆H₁₈F₃N₅O₆S₂
SMILES	O=C(OC)C=1SC(=CC1)S(=O)(=O)NC=2C=CC(=CC2)C3=NC(=NO3)C=4C=CN=C(C4)NC5=CC=C(OC(F)(F)F)C=C5
Target	GSK-3

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

162649584 ↗

Key Properties

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No computed properties available.

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