HDAC4 Rabbit mAb [KD Validated] Antibody

SKU: orb1951357

Description

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

Images & Validation

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Item 1 of 2

Tested Applications	ICC, WB
Dilution range	WB 1:1000~1:2000 ICC/IF 1:50~1:200
Reactivity	Human

Key Properties

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Antibody Type	Recombinant Antibody
Host	Rabbit
Clonality	Monoclonal
Isotype	Rabbit IgG
Clone No.	2.00E+13
Immunogen	A synthesized peptide derived from human HDAC4
Target	HDAC4
Purification	Affinity-chromatography
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Form/Appearance	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer	For research use only

Alternative Names

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Histone deacetylase 4; HD4; HDAC4; AHO3; BDMR;

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HDAC4 Rabbit mAb [KD Validated] Antibody

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

All Lanes: HDAC4 Antibody at 1/500 dilution. Lane 1: Hela lysate. Proteins at 20 ug per lane, Secondary: Goat Anti-Rabbit IgG (HRP) at 1/20000 dilution. Predicted band size: 140 kDa, Observed band size: 140 kDa.

Quick Database Links

Gene Symbol

HDAC4

UniProt

P56524

UniProt Details

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No UniProt data available

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Protocol Information

Western Blot (IB, immunoblot)

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ICC

Immunocytochemistry

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