Histone H3 (acetyl K56) Rabbit mAb [KD Validated] Antibody

SKU: orb1951870

Description

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Images & Validation

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Item 1 of 4

Tested Applications	ICC, IHC, WB
Dilution range	WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Reactivity	Human, Mouse, Rat

Key Properties

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Antibody Type	Recombinant Antibody
Host	Rabbit
Clonality	Monoclonal
Isotype	Rabbit IgG
Immunogen	A synthesized peptide derived from human Histone H3 (acetyl K56)
Purification	Affinity-chromatography
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Form/Appearance	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer	For research use only

Alternative Names

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H3/a; H3/c; H3/d; H3/f; H3/h; H3/i; H3/j; H3/k; H3/l; H31; HIST1H3A; histone H3.1;

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Histone H3 (acetyl K56) Rabbit mAb [KD Validated] Antibody

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

Immunofluorescent analysis of Hela cells, using Histone H3 (acetyl K56) Antibody.

Immunohistochemical analysis of paraffin-embedded human colon, using Histone H3 (acetyl K56) Antibody.

Western blot analysis of Histone H3 (acetyl K56) expression in C6 cell lysate, treated with TSA.

Quick Database Links

UniProt

P68431

UniProt Details

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No UniProt data available

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Protocol Information

Western Blot (IB, immunoblot)

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IHC

Immunohistochemistry

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ICC

Immunocytochemistry

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