Human BACE-1 Protein

SKU: orb257210

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Description

Human BACE-1, Tag Free is expressed from human 293 cells (HEK293). It contains AA Thr 22 - Thr 457 (Accession # NP_036236.1).

Research Area

Cell Biology

Images & Validation

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Application Notes	This protein carries no "tag". The protein has a calculated MW of 49.0 kDa. The protein migrates as 53-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

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Expression System	HEK293
Target	BACE-1
Reactivity	Human
Tag	Native
Expression Region	Thr 22 - Thr 457
Endotoxins	1.0 EU per μg
Conjugation	Unconjugated
MW	49.0 kDa
Purity	98%

Storage & Handling

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Storage	-20°C
Form/Appearance	Powder
Buffer/Preservatives	50 mM Tris, pH 8.0
Expiration Date	6 months from date of receipt.
Disclaimer	For research use only

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SDS-PAGE analysis of Human BACE-1 protein

Quick Database Links

Gene Symbol

BACE-1

UniProt

NP_036236.1

RefSeq (Protein):NP_036236.1

UniProt Details

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No UniProt data available

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

Protein	NP_036236.1

Documents Download

Datasheet

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Protocol Information

Protein Handling and Storage Guide

Protein Handling Guide

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Find More Protocols

Peters-Libeu, Clare et al. sAβPPα is a Potent Endogenous Inhibitor of BACE1 J Alzheimers Dis, 47, 545-555 (2015)

PubMed: 26401691