Human IL-1RA Protein, Tag Free (MALS verified)

SKU: orb3158166

Description

Interleukin-1 receptor antagonist (IL-1RA) is a naturally occurring anti-inflammatory antagonist of interleukin-1 family of pro-inflammatory cytokines. It competes with IL-1α and IL-1β to bind IL-1R1, thereby acting as an endogenous inhibitor of the IL-1 signaling pathway. IL‐1RA has been connected with a variety of diseases, including cardiovascular disease, type II diabetes, carcinoma, and joint diseases.

Images & Validation

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Application Notes	This protein carries no "tag". The protein has a calculated MW of 17.3 kDa. The protein migrates as 15-16 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

Key Properties

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Expression System	E. coli
Target	IL-1RA
Reactivity	Human
Tag	Native
Molecular Weight	17.3 kDa
Expression Region	Arg 26 - Glu 177
Purity	95%
Endotoxins	1.0 EU per μg
Conjugation	Unconjugated

Storage & Handling

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Storage	-20°C
Form/Appearance	Powder
Buffer/Preservatives	PBS, pH 7.4
Expiration Date	6 months from date of receipt.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

IL-1RA

RefSeq:P18510

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

RefSeq	P18510

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