IGF-BP6 Recombinant Protein

SKU: orb1230789

Description

Research Area

Cancer Biology, Signal Transduction

Images & Validation

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Key Properties

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Biological Activity	Biological activity was determined by its ability to inhibit IGF - II induced proliferation of human MCF - 7 cells. The expected ED50 for this effect is 0.1 - 0.4 μg/mL.
Target	IGFBP6
Protein Sequence	RCPGCGQGVQ AGCPGGCVEE EDGGSPAEGC AEAEGCLRRE GQECGVYTPN CAPGLQCHPP KDDEAPLRAL LLGRGRCLPA RAPAVAEENP KESKPQAGTA RPQDVNRRDQ QRNPGTSTTP SQPNSAGVQD TEMGPCRRHL DSVLQQLQTE VYRGAQTLYV PNCDHRGFYR KRQCRSSQGQ RRGPCWCVDR MGKSLPGSPD GNGSSSCPTG SSG
Purity	Greater than 95% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Storage & Handling

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Storage	The lyophilized IGF-BP6 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IGF-BP6 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing IGF-BP6 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Form/Appearance	Lyophilized
Disclaimer	For research use only

Alternative Names

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IBP6, IBP6, Insulin-like growth factor-binding protein 6, IBP-6

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Quick Database Links

Gene Symbol

IGFBP6

UniProt

P24592

RefSeq (Protein):NP_002169.1

UniProt Details

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No UniProt data available

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

Protein	NP_002169.1

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