IL-6 (Interleukin-6) / Interferon beta-2 (Hybridoma Growth Factor) Antibody

SKU: orb2309588

Description

Images & Validation

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Item 1 of 4

Tested Applications	IHC
Reactivity	Human

Key Properties

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Host	Mouse
Clonality	Monoclonal
Isotype	IgG2
Clone No.	IL6/4643
Immunogen	Recombinant fragment (around aa1-200) of human IL-6 protein (exact sequence is proprietary)
Target	IL-6
Source/Expression System	Bioreactor
Molecular Weight	21kDa
Purification	Protein A
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Form/Appearance	200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
Disclaimer	For research use only

Alternative Names

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B-cell stimulatory factor 2 (BSF-2); CTL differentiation factor (CDF); Cytotoxic T cell differentiation factor; Hepatocyte stimulating factor (HSF); HPGF; Hybridoma growth factor Interferon beta-2; Hybridoma plasmacytoma growth factor; IFN-beta-2 (IFNB2)

Quality Guarantee

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IL-6 (Interleukin-6) / Interferon beta-2 (Hybridoma Growth Factor) Antibody

Analysis of Protein Array containing more than 19000 full-length human proteins using IL-6-Monospecific Mouse Monoclonal Antibody (IL6/4643). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Formalin-fixed, paraffin-embedded human COVID positive lung stained with IL-6 Mouse Monoclonal Antibody (IL6/4643) at 2 ug/ml. HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min.

Formalin-fixed, paraffin-embedded human kidney stained with IL-6 Mouse Monoclonal Antibody (IL6/4643) at 2 ug/ml. Inset: PBS instead of primary antibody; secondary only negative control.

SDS-PAGE Analysis of Purified CD161 Mouse Monoclonal Antibody (KLRB1/8910). Confirmation of Purity and Integrity of Antibody.

Quick Database Links

Gene Symbol

IL-6

UniProt

P05231

UniProt Details

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No UniProt data available

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Protocol Information

IHC

Immunohistochemistry

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