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Imiquimod 2HCl

SKU: orb2283882

Description

Imiquimod 2HCl is a synthetic TLR7 agonist that functions as an immune response modifier with demonstrated antiviral and antitumor properties. It is widely utilized in preclinical research for modeling psoriasis-like inflammation in mice and for investigating conditions such as periorbital skin cancer, pemphigus foliaceus, and COVID-19 pathogenesis.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number2995277-02-4
MW313.23
Purity99.41%
FormulaC14H18Cl2N4
SMILESNC1=NC2=C(C3=C1N=CN3CC(C)C)C=CC=C2.Cl.Cl
TargetAutophagy,Antiviral,SARS-CoV,HSV,TLR

Bioactivity

In Vitro
In 8-11 week-old BALB/c mice, Imiquimod 2HCl (3.125 mg/day for 6 days; applied to the skin) induces signs of erythema, scaling, and thickening on the mice's back skin, accompanied by hyperproliferative keratinocytes and disrupted epidermal differentiation.

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Imiquimod 2HCl(99011-02-6 Free base), Imiquimod2HCl(99011026Freebase), antiviral;TLR7
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Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

Imiquimod 2HCl (orb2283882)

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1 mg
¥ 3,120.00
5 mg
¥ 6,890.00
10 mg
¥ 9,620.00
25 mg
¥ 14,560.00
50 mg
¥ 19,890.00
100 mg
¥ 26,130.00
DispatchUsually dispatched within 5-10 working days
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