Imiquimod hydrochloride

SKU: orb1909165

Description

Imiquimod hydrochloride (R 837 hydrochloride) is a selective TLR7 agonist and immune modulator with antiviral and antitumor properties. It is widely used in research to model psoriasis and study conditions like genital warts, skin cancer, and COVID-19, employing both in vitro assays and in vivo animal models.

Research Area

Immunology & Inflammation

Images & Validation

−

Key Properties

−

CAS Number	99011-78-6
MW	276.77
Purity	99.98%
Formula	C₁₄H₁₇ClN₄
SMILES	Cl.CC(C)Cn1cnc2c(N)nc3ccccc3c12
Target	TLR
Solubility	DMSO:5 mg/mL (18.07 mM);Saline:1.82 mg/mL (6.58 mM);Methanol:15 mg/mL (54.2 mM);Ethanol:1 mg/mL (3.61 mM);H2O:2 mg/mL (7.23 mM)

Bioactivity

−

In Vivo	Imiquimod hydrochloride stimulates innate immune responses by inducing synthesis and release of cytokines, including interferon-α (IFN-α), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α). Read more...

Storage & Handling

−

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

−

R 837 hydrochloride, R837 hydrochloride, R-837 hydrochloride, TLR7, Imiquimod HCl

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Compound Identifiers

PubChem CID

13982876 ↗

Key Properties

−

No computed properties available.

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols