Immunology/Inflammation related Antibody

SKU: orb3169615

Description

PF-5212374 (TRU-015) is a CD20-directed small modular immunopharmaceutical (SMIP). Unlike traditional full-length antibodies, TRU-015 is a dimeric fusion protein comprising a single-chain Fv (scFv) binding domain coupled to the hinge and Fc regions of IgG1. It specifically binds to CD20 on the surface of B cells, activating Immunology/Inflammation-related signaling pathways to effectively mediate antibody-dependent cellular cytotoxicity (ADCC) and direct induction of apoptosis, resulting in the depletion of both normal and malignant B cells.

Images & Validation

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Key Properties

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Antibody Type	Inhibitor Antibody
Target	Immunology/Inflammation related
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Immunology/Inflammation related

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