Integrin alpha V Rabbit mAb [KD Validated]

SKU: orb1951048

Description

The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Images & Validation

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Item 1 of 2

Tested Applications	ICC, IHC, IP, WB
Dilution range	WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:40
Reactivity	Human, Mouse, Rat

Key Properties

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Antibody Type	Recombinant Antibody
Host	Rabbit
Clonality	Recombinant
Isotype	Rabbit IgG
Immunogen	A synthesized peptide derived from human Integrin alpha V
Purification	Affinity-chromatography

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Form/Appearance	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer	For research use only

Alternative Names

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CD51; integrin alpha V beta 3; ITGAV; Msk8; VNRA; VTNR;

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Integrin alpha V Rabbit mAb [KD Validated]

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

Western blot analysis of Integrin alpha V expression in (1) A549 cell lysate; (2) Mouse spleen lysate; (3) Rat brain lysate.

Quick Database Links

UniProt

P06756

UniProt Details

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No UniProt data available

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Protocol Information

Western Blot (IB, immunoblot)

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IHC

Immunohistochemistry

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ICC

Immunocytochemistry

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Immunoprecipitation

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