Itacnosertib (hydrocholide)

SKU: orb2283534

Description

Itacnosertib hydrochloride is a small molecule inhibitor targeting JAK2, ACVR1/ALK2, and ALK5 kinases. It is used in research to investigate fibrotic diseases and myeloproliferative disorders, with studies demonstrating its activity in both cellular assays and animal models.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

−

Key Properties

−

CAS Number	2409543-84-4
MW	505.01
Formula	C₂₆H₂₉ClN₈O
SMILES	O(C)C1=C(C=CC(NC=2N=C(NC3=C(N=CC=C3)C4=CC=CC=N4)C=CN2)=C1)N5CCN(C)CC5.Cl
Target	Akt,Others,ALK,FLT,TGF-beta/Smad,JAK,mTOR,STAT,PI3K

Storage & Handling

−

Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Compound Identifiers

PubChem CID

170453359 ↗

Key Properties

−

No computed properties available.

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols