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KGYY15

SKU: orb2563670

Description

KGYY15 is a mouse-derived peptide targeting CD40, exhibiting weak antagonism of the CD40-CD40L interaction (IC50 >1 mM) while paradoxically inducing NF-κB pathway activation (33% at 100 µM). This unique profile makes it a useful research tool for studying CD40 signaling complexity in both cellular and animal models of immune regulation.

Research Area

Cell Biology

Images & Validation

Key Properties

TargetTNF
CAS Number1690215-31-6
MW1817.12
FormulaC84H129N21O22S
SMILESC([C@H](NC([C@@H](NC([C@@H](NC([C@H](C(C)C)N)=O)CC(C)C)=O)CCC(N)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(N)=O)C(O)=O)=O)CO)=O)CCCCN)=O)CCSC)=O)[C@@H](C)O)=O)=O)=O)=O)CCCCN)=O)CCCCN)=O)C)=O)C=3C=4C(NC3)=CC=CC4

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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KGYY15 (orb2563670)

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