KMT6 / EZH2 Rabbit mAb [KD Validated] Antibody

SKU: orb1951271

Description

Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively.

Images & Validation

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Tested Applications	WB
Dilution range	WB 1:500~1:2000
Reactivity	Human

Key Properties

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Antibody Type	Recombinant Antibody
Host	Rabbit
Clonality	Monoclonal
Isotype	Rabbit IgG
Immunogen	A synthesized peptide derived from human KMT6 / EZH2
Purification	Affinity-chromatography
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Form/Appearance	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer	For research use only

Alternative Names

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EZH1; EZH2; EZH2b; KMT6; KMT6A;

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KMT6 / EZH2 Rabbit mAb [KD Validated] Antibody

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

Western blot analysis of KMT6 / EZH2 expression in Hela cell lysate.

Quick Database Links

UniProt

Q15910

UniProt Details

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No UniProt data available

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Protocol Information

Western Blot (IB, immunoblot)

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