Lenzilumab Antibody

SKU: orb1980692

Description

Lenzilumab (KB 003) is a humanized granulocyte-macrophage colony-stimulating factor (GM-CSF) neutralizing antibody that directly binds to GM-CSF and prevents signaling through its receptor, and can be used to study COVID-19.

Research Area

Infectious Disease & Virology, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	1229575-09-0
Purity	95.00%
Target	SARS-CoV,c-Fms

Bioactivity

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In Vivo	Intraperitoneal injection of 10 mg/kg Lenzilumab once daily for 10 days improved its antitumor effect in NSG mice by inhibiting GM-CSF without impairin the cellular function of CAR-T and a the same time. Read more...

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Disclaimer	For research use only

Alternative Names

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KB 003, KB003

Quality Guarantee

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Gene Symbol

SARS-CoV,c-Fms

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