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Licarin A

SKU: orb1705457

Description

Licarin A is a naturally occurring lignan with demonstrated anti-inflammatory activity. It functions by inhibiting the PKCα/βII and p38 MAPK signaling pathways, which subsequently reduces TNF-α and prostaglandin D2 release as well as COX-2 expression. This compound is utilized in vitro for researching inflammation mechanisms in models such as macrophages.

Research Area

Cell Biology, Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number51020-86-1
MW326.39
Purity99.50%
FormulaC20H22O4
SMILESO(C)C1=C2C([C@@H](C)[C@@H](O2)C3=CC(OC)=C(O)C=C3)=CC(/C=C/C)=C1
TargetProstaglandin Receptor,TNF,p38 MAPK,COX
SolubilityDMSO:40 mg/mL (122.55 mM);H2O:< 0.1(insoluble)

Storage & Handling

Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
DisclaimerFor research use only

Alternative Names

(-)-Licarin A, NSC 370989, NSC-370989, NSC370989, Licarin A

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Licarin A (orb1705457)

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% DMSO +
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Available Sizes

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1 mg
¥ 1,690.00
5 mg
¥ 3,120.00
10 mg
¥ 4,420.00
25 mg
¥ 7,020.00
DispatchUsually dispatched within 5-10 working days
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