Lintuzumab Biosimilar (Siglec-3 / CD33 Reference Antibody）

SKU: orb2703720

Description

Lintuzumab (HUM-195) is an anti-CD33 humanized monoclonal antibody. Lintuzumab reduces the production of TNFα-induced pro-inflammatory cytokines and chemokines by AML cells. Lintuzumab promotes tumor cell killing through antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis (ADCP) activities against MDR? and MDR+ AML cell lines and primary AML patient samples. Lintuzumab enhances survival and reduces tumor burden in mice.

Images & Validation

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Key Properties

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Antibody Type	Biosimilar Antibody
Clonality	Monoclonal
Target	Lintuzumab Biosimilar（Anti-Siglec-3 / CD33 Reference Antibody）
Purity	>98%
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Disclaimer	For research use only

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Gene Symbol

Lintuzumab Biosimilar（Anti-Siglec-3 / CD33 Reference Antibody）

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