Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

LYN-1604

SKU: orb1690052

Description

LYN-1604 is a potent and selective small molecule activator of ULK1. It induces cell death through concurrent autophagy and apoptosis, involving key mediators like ATF3, RAD21, and caspase-3. This compound is a valuable research tool for investigating programmed cell death mechanisms in both in vitro and in vivo cancer models.

Research Area

Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number2088939-99-3
MW584.62
FormulaC33H43Cl2N3O2
SMILESC(CN1CCN(C(CN(CC(C)C)CC(C)C)=O)CC1)(OCC2=CC3=C(C=C2)C=CC=C3)C4=C(Cl)C=C(Cl)C=C4
TargetAutophagy|||Apoptosis
SolubilityDMSO:46 mg/mL (78.68 mM);H2O:90 mg/mL (153.95 mM)

Bioactivity

Target IC50
ULK1:18.94 nM(EC50)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Inhibitor, inhibit, negative, LYN1604, LYN-1604, LYN 1604, breast, activator, cancer, Autophagy, anti-tumor, Apoptosis, TNBC, triple, Unc-51 like kinase, ULK1, ULK

Similar Products

  • LYN-1604 hydrochloride [orb1691128]

    2216753-86-3

    621.08

    C33H44Cl3N3O2

    50 mg, 100 mg
  • LYN-1604 dihydrochloride [orb1298617]

    99.80% (May vary between batches)

    2310109-38-5

    657.54

    C33H45Cl4N3O2

    5 mg, 10 mg, 25 mg, 50 mg, 1 mg, 100 mg, 1 ml x 10 mM (in DMSO), 200 mg
  • LYN-1604 2HCl 2216753-86-3(HCl) [orb1219320]

    2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 g
  • LYN-1604 [orb1225706]

    >98% (HPLC)

    2088939-99-3

    584.626

    C33H43Cl2N3O2

    2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg, 1 g, 200 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 150.00
2 mg
$ 200.00
5 mg
$ 300.00
1 ml x 10 mM (in DMSO)
$ 340.00
10 mg
$ 420.00
25 mg
$ 680.00
50 mg
$ 870.00
100 mg
$ 1,250.00
DispatchUsually dispatched within 5-10 working days
Bulk Enquiry