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ML-240

SKU: orb1226489

Description

ML240 is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM); blocks degradation of p97-dependent proteasome substrate with an IC50 of 0.9 uM; induces caspases 3 and 7 and potently blocked proliferation in HCT15 and SW403 cells.

Images & Validation

Key Properties

CAS Number1346527-98-7
MW396.4445
Purity>98% (HPLC)
FormulaC23H20N6O
SMILESCOC1=CC=CC2=C(NCC3=CC=CC=C3)N=C(N4C5=CC=CC=C5N=C4N)N=C12
Targetp97
SolubilityDMSO: 16.5 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

ML 240 | ML-240

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Protocol Information

Available Sizes

Select a size below

2 mg
$ 90.00
5 mg
$ 130.00
10 mg
$ 200.00
25 mg
$ 400.00
50 mg
$ 680.00
100 mg
$ 990.00
500 mg
$ 2,090.00