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ML240

SKU: orb1304103

Description

ML240 is a potent and selective small molecule inhibitor that targets the AAA+ ATPase p97 (VCP) by competitively binding to its ATPase sites. It is widely used in cancer and neurodegenerative disease research to probe p97 function in protein homeostasis, with applications in both cellular and in vivo models.

Research Area

Protein Biochemistry

Images & Validation

Key Properties

CAS Number1346527-98-7
MW396.44
Purity99.66% (May vary between batches)
FormulaC23H20N6O
SMILESCOc1cccc2c(NCc3ccccc3)nc(nc12)-n1c(N)nc2ccccc12
Targetp97
SolubilityDMSO:50 mg/mL (126.12 mM);10% DMSO+90% Corn Oil:2.5 mg/mL (6.31 mM)

Bioactivity

Target IC50
p97:100 nM.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

VCP, Cdc48, p97, P97, inhibit, ML240, ML-240, ML 240, Inhibitor

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  • ML-240 [orb1226489]

    >98% (HPLC)

    1346527-98-7

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    C23H20N6O

    2 mg, 5 mg, 10 mg, 50 mg, 100 mg, 500 mg, 1 g, 25 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 80.00
2 mg
$ 90.00
5 mg
$ 120.00
1 ml x 10 mM (in DMSO)
$ 130.00
10 mg
$ 160.00
25 mg
$ 290.00
50 mg
$ 480.00
100 mg
$ 680.00
500 mg
$ 1,460.00
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