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Molnupiravir

SKU: orb1689082

Description

Molnupiravir

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number2492423-29-5
MW329.31
Purity99.98%
FormulaC13H19N3O7
SMILESCC(C)C(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc\c(=N/O)[nH]c1=O
TargetSARS-CoV,Influenza Virus
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.07 mM);DMSO:257.5 mg/mL (781.94 mM)

Bioactivity

In Vivo
METHODS: Molnupiravir (MK-4482) (EIDD-2801) (50, 150, or 500 mg/kg, orally, every 12 hours) was used to prophylactically treat mice infected with SARS-CoV and observe its effects in mice. RESULTS Molnupiravir has potent antiviral activity and is able to prevent SARS-CoV replication and disease.
In Vitro
METHODS: RD, Huh7, and Vero cells were treated with Molnupiravir (MK-4482) (EIDD-2801) (1, 10, 100 μM) for cytopathic effect (CPE) protection assay. RESULTS EIDD-2801 showed stable CPE protection potential in a dose-dependent manner in multiple cell lines infected with EV-A71 virus; the value against EV-A71 virus was 70.12±4.40μM in RD cells; 88.52±3.18μM in Vero cells, and 35.64±0.47μM in Huh7 cells.

Storage & Handling

Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

2349386-89-4, Molnupiravir, MK4482, MK-4482, MK 4482, InfluenzaVirus, Influenza virus, Influenza Virus, Lagevrio, EIDD 2801, EIDD2801, EIDD-2801, SARSCoV, SARS-CoV

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Key Properties

No computed properties available.

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Protocol Information

Molnupiravir (orb1689082)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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5 mg
¥ 1,040.00
10 mg
¥ 1,300.00
1 ml x 10 mM (in DMSO)
¥ 1,430.00
25 mg
¥ 1,560.00
50 mg
¥ 2,210.00
100 mg
¥ 3,120.00
200 mg
¥ 5,460.00
500 mg
¥ 10,790.00
1 g
¥ 14,560.00
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