Momelotinib Mesylate

SKU: orb1707409

Description

Momelotinib Mesylate is a potent and selective small molecule inhibitor targeting JAK1 and JAK2 kinases, exhibiting approximately 10-fold lower activity against JAK3. It has been utilized in research models of myelofibrosis and anemia to investigate its effects on cytokine signaling, splenomegaly, and hepcidin modulation in both cellular and animal studies.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

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Key Properties

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CAS Number	1056636-07-7
MW	510.57
Formula	C₂₄H₂₆N₆O₅S
SMILES	CS(O)(=O)=O.O=C(NCC#N)c1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1
Target	JAK,Autophagy

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

78357762 ↗

Key Properties

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No computed properties available.

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