N-Formyl-Met-Leu-Phe-Lys

SKU: orb1296725

Description

N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a potent and selective formyl peptide receptor 1 (FPR1) agonist. It is widely used in research to study neutrophil chemotaxis and activation in vitro and to model localized inflammation in vivo, providing a tool to investigate innate immune responses.

Images & Validation

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Key Properties

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CAS Number	67247-11-4
MW	565.73
Purity	99.7%
Formula	C₂₇H₄₃N₅O₆S
SMILES	[C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@H](CCSC)NC=O)=O)CC(C)C)=O)C(N[C@@H](CCCCN)C(O)=O)=O
Target	Others
Solubility	H2O:Soluble

Bioactivity

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Target IC50	FPR1:3.5 nM (EC50)\|FPR2:6.7 μM (EC50)\|FPR2 (D2817.32G):0.88 μM (EC50)

Storage & Handling

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Storage	keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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NFormylMetLeuPheLys, N-Formyl-Met-Leu-Phe-Lys, inhibit, Inhibitor, N Formyl Met Leu Phe Lys, fMLFK, FPR1, FPR2

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Compound Identifiers

PubChem CID

9894161 ↗

Key Properties

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No computed properties available.

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