Otilimab Antibody

SKU: orb1980323

Description

Otilimab (GSK 3196165) is a humanized monoclonal antibody against granulocyt-macrophage colony-stimulating factor (GM-CSF). Otilimab has anti-inflammatory activity, regulates the biological function of GM-CSF by blocking the interaction between GM-CSF and its cell surface receptors, and can be used in studies to treat severe COVID-19 pneumonia.

Research Area

Signal Transduction

Images & Validation

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Key Properties

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CAS Number	1638332-55-4
MW	142.22 kDa
Purity	SDS-PAGE:95% SEC-HPLC:95%
Target	CSF-1R,c-Fms

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Disclaimer	For research use only

Alternative Names

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Otilimab, MOR 103, MOR103, MOR-103, GSK 3196165, GSK-3196165, GSK3196165, CSF1R, CSF-1R

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Gene Symbol

CSF-1R,c-Fms

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